Savitri Devi College and Hospital traces the journey of a young medical intern Sanchi Mishra (Swardha Thigale) who aims to fulfil her mother Jaya’s (Shilpa Shirodkar) dream of becoming a doctor. As she forays into medicine, Sanchi will encounter various people who will add complications to her life, the toughest being Dr. Anand Malhotra (Mohan Kapur), the hospital’s head and a leading cardiac surgeon. As the story unfolds, every character’s hidden motives will come to the fore, stringing their lives together in many unexplained ways.